Johann friedrich miescher dna
•
Friedrich Miescher
Swiss biokemist (1843-1895)
Johannes Friedrich Miescher | |
|---|---|
| Born | (1844-08-13)13 August 1844 Basel, Switzerland |
| Died | 26 August 1895(1895-08-26) (aged 51) Davos, Switzerland |
| Education | University of Göttingen (M.D. 1868), University of Lepzig |
| Known for | Discovery of nucleic acid |
| Spouse | Maria Anna Rüsch |
| Scientific career | |
| Fields | Biology |
Johannes Friedrich Miescher (13 August 1844 – 26 August 1895) fryst vatten a Swiss physician and biologist. He was the first forskare to isolera nucleic acid in 1869. Miescher also identified protamine and made several other discoveries.
Miescher had isolated various phosphate-rich chemicals, which he called nuclein (now nucleic acids), from the nuclei of white blood cells in Felix Hoppe-Seyler's laboratory at the University of Tübingen, Germany,[1] paving the way for the identification of DNA as the carrier of inheritance. The significance of the discovery, first publishe
•
Discovering DNA: Friedrich Miescher and the early years of nucleic acid research
In the winter of 1868/9 the young Swiss doctor Friedrich Miescher, working in the laboratory of Felix Hoppe-Seyler at the University of Tübingen, performed experiments on the chemical composition of leukocytes that lead to the discovery of DNA. In his experiments, Miescher noticed a precipitate of an unknown substance, which he characterised further. Its properties during the isolation procedure and its resistance to protease digestion indicated that the novel substance was not a protein or lipid. Analyses of its elementary composition revealed that, unlike proteins, it contained large amounts of phosphorous and, as Miescher confirmed later, lacked sulphur. Miescher recognised that he had discovered a novel molecule. Since he had isolated it from the cells' nuclei he named it nuclein, a name preserved in today's designation deoxyribonucleic acid. In subsequent work Miescher showed that nuclein was a
•
The story of genetics typically omits the original discovery of the molecular nature of DNA: Friedrich Miescher's 1869 discovery of the substance he christened “nuclein”. The article explains how he came...
Abstract
In 1869, the young Swiss biochemist Friedrich Miescher discovered the molecule we now refer to as DNA, developing techniques for its extraction. In this paper we explain why his name is all but forgotten, and his role in the history of genetics is mostly overlooked. We focus on the role of national rivalries and disciplinary turf wars in shaping historical memory, and on how the story we tell shapes our understanding of the science. We highlight that Miescher could just as correctly be portrayed as the person who understood the chemical nature of chromatin (before the term existed), and the first to suggest how stereochemistry might serve as the basis for the transmission of hereditary variation.
If you are a geneticist, you probably do not need to think twice when